GoAnywhere was designed to be flexible enough to fit pretty much any business need when it comes to melding into a Network Architecture. With that being said, there is no "better" way to fit it into a pre-defined network.
We have people using DFS Servers and connecting both GAMFT servers to this File Server. Then, when necessary, pointing both to the D/R version. A simple option.
We also have people using an external servers (NFS, Isilon, SAN, etc) and utilizing the mirroring images there. So, there are so many options that could be utilized in this scenario.