AS2 utilizes multiple SSL certificates for encryption, signatures and MDNs. It also protects the HTTP communication with SSL. Then when adding networking considerations for firewalls and application setup it can make AS2 seem complex to get started.
In the User Guide we have good documentation as well as an AS2 Quick Start section. However, we would recommend that you reach out to our support staff as they are more than willing to get you up and running in no time.