I used Edit Layout to select one wide column on My Dashboard. Now when I select other layout options, I only see the one column, that gets skinnier when I select the other layouts. Using Chrome 44.0.2403.130. I tried clearing the cache and restarting Chrome. Also tested with IE 11, same result.
Edit: I figured it out. After switching back to a multi-column layout, you have to drag and drop the gadgets back to the other columns. I expected them to go back automatically.